Systemic Sclerosis: Background, Diagnosis And Treatment (part 2 of 2)

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What Can Happen To A Systemic Sclerosis Patient?

A patient with systemic sclerosis can have limited functions in various organs at the same time, most of the time being with the heart, kidneys and lungs. With that, a patient will also show the illness through some visible factors that can be seen especially in the face, neck, fingers, elbows, knees and toenails. If not managed effectively, systemic sclerosis can spread onto other organs or could develop into another disease other than scleroderma.

When it comes to systemic sclerosis, renal and lung related problems are usually the common causes for mortalities. Pulmonary hypertension, which is one of the most common causes of deaths in systemic sclerosis accounts for about 12% of all deaths.

How Can Systemic Sclerosis Be Treated?

Since the cause of scleroderma is not yet known, there is also no known medication for scleroderma instead, the approach for treating systemic sclerosis is patient specific and would depend on which organs are affected by it. Treatment is also focused for limiting the damages done by scleroderma and for alleviating symptoms rather than completely remove scleroderma from a patient.

Treatment is usually done by medications that would vary depending on the case and on which organs are affected. Alternative medications are also given to people who cannot be helped or would develop side effects from the medications that were first taken. For some cases especially for those having problems with organ function, they would have to undergo therapy that would attempt to restore normal organ activity.

Systemic Sclerosis: Background, Diagnosis And Treatment (part 1 of 2)

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Definition

Scleroderma comes mainly in two forms, the localized form of which would only affect a single area and another from which would affect internal organs known as systemic sclerosis. The localized form is also known as “morphea” and although it could disable a patient, it would not be fatal most of the time. Systematic sclerosis however, since it interferes with the internal organs and their functions would be fatal most of the time. Common cases of death from systemic sclerosis are renal and lung related cases.

Scleroderma occurs when your antibodies would attack your tissues instead of protecting them that in turn would lead to the development of scar tissue on the affected areas or thicken it. Women are four times more likely to develop this disease than men are and it usually develops within 30 to 40 years of age. This disease is inherent in the Native American Choctaw race and African-American women and rarely occurs to North Asians. It also rarely occurs in children.

What Can Cause Systemic Sclerosis?

It is known that scleroderma is an autoimmune disease however, only part of the pathogenesis is understood and because of that, medical experts have developed various theories that would refer to the causes of scleroderma. One theory would say that scleroderma is largely environmental and is brought about by unwanted factors in the environment such as bacteria and viruses while another would say that it is genetic and with that, heredity plays a big role.

Some of the substances which are suspected to cause scleroderma are insecticides, epoxy resin, appetite suppressants, silicone implants, drugs and some amino acid compounds. One medical expert also said that the fetal matter left after pregnancy that is still running in the bloodstream can also cause systemic scleroderma. These theories however are not yet proven.

Finding a Friendly Mortgage Rate for Refinancing in Arizona (part 2 of 2)

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Your current credit standing could also be very useful in helping you get good mortgage refinance rates in Arizona.  If you haven't had any problems with your credit in the past, your lenders are more than inclined to offer you a good deal.

Always compare lenders.
In Arizona, as in everywhere else, make sure you talk to multiple lenders.  The idea is to find the best rate possible for your type of loan and credit history.  Look for locally advertised mortgages in Arizona from at 3 or 4 different lenders.

Remember that refinancing does cost money over the long term and if you don't get good rates, you could end up paying higher payments each month.

Find out about closing costs.
Getting refinanced means going through the loan process all over again.  You will have to pay for fees, certain charges and closing costs.  If you're taking out a mortgage refinance loan in Arizona, find out how much you'll be paying because this could significantly burden your finances – at least temporarily.

Got good credit standing?  You could take advantage of low advertised rates.
The low, low figures you find advertised on a lender's website or classified ads are meant for borrowers who have above average credit standing.  If you fall below this category or have less than the ideal credit score, you might not be offered these borrower-friendly mortgage refinance rates.

If you're borrowing for refinancing in Arizona, check your credit first.  The more reliable you are as a payer, the more likely you will be rewarded with great mortgage refinance rates.

Finding a Friendly Mortgage Rate for Refinancing in Arizona (part 1 of 2)

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If you're looking to take out a refinancing loan and are living in Arizona, you could take advantage of the good mortgage rates currently on the table.  In December 2008, the average going rates for 30-year FHA refinancing mortgages dipped nearly 20 basis points, landing at a friendly mortgage rate of 5.73%.  Compare that with the average mortgage refinance rate of about 6.4% to 6.6% just recently.  Since it's a good time to consider having your mortgage refinanced in Arizona, here are some tips on finding the best mortgage rates around:

Consider what matters to you.
Determine the factors that will make a mortgage refinance rate advantageous for you.  After all, your goal is to find the one that: a) you can afford and b) give you significant savings over the long term.  Once you get a quote, do a few calculations to determine if the mortgage refinance rate is a good deal for you.

Consider mortgage type and shorter payment periods.
If you have the resources, it would be advantageous for you to shorten the life of your loan.  If you choose a 15-year payment program, for example, you will get lower mortgage rates than if you took out a loan for a 30-year period loan.

Use your equity.
If you take care of your home now, you will be able to reap the rewards later.  Your home's equity will increase as its market value increases.  You could help this along by making sure that the home is well cared for.  Doing a few maintenance repairs here and there can mean the world of difference in the future.

Furthermore, you could raise your equity and enjoy low mortgage refinance rates later once you've paid up a good amount of your current mortgage balance.  This decrease will get you a good deal on your rates.